Broad RNA Interference-Mediated Antiviral Immunity and Virus-Specific Inducible Responses in Drosophila. Kemp C, Mueller S, Goto A, Barbier V, Paro S, Bonnay F, Dostert C, Troxler L, Hetru C, Meignin C, Pfeffer S, Hoffmann JA, Imler JL. J Immunol. 2012 Dec 19.
MiR-20a regulates ASK1 expression and TLR4-dependent cytokine release in rheumatoid fibroblast-like synoviocytes. Philippe L, Alsaleh G, Pichot A, Ostermann E, Zuber G, Frisch B, Sibilia J, Pfeffer S, Bahram S, Wachsmann D, Georgel P. Ann Rheum Dis. 2012 Oct 27.
miR-122 acts as a tumor suppressor in hepatocarcinogenesis in vivo. Zeisel MB, Pfeffer S, Baumert TF. J Hepatol. 2012 Oct 17.
Degradation of cellular mir-27 by a novel, highly abundant viral transcript is important for efficient virus replication in vivo. Marcinowski L, Tanguy M, Krmpotic A, Rädle B, Lisnić VJ, Tuddenham L, Chane-Woon-Ming B, Ruzsics Z, Erhard F, Benkartek C, Babic M, Zimmer R, Trgovcich J, Koszinowski UH, Jonjic S, Pfeffer S, Dölken L. PLoS Pathog. 2012 Feb ;8(2):e1002510
Deregulation of type I IFN-dependent genes correlates with increased susceptibility to cytomegalovirus acute infection of dicer mutant mice.Ostermann E, Tuddenham L, Macquin C, Alsaleh G, Schreiber-Becker J, Tanguy M, Bahram S, Pfeffer S, Georgel P. PLoS One. 2012 ;7(8):e43744.
Reconstitution of the entire hepatitis C virus life cycle in nonhepatic cells. Da Costa D, Turek M, Felmlee DJ, Girardi E, Pfeffer S, Long G, Bartenschlager R, Zeisel MB, Baumert TF. J Virol. 2012 Nov ;86(21):11919-25.
Case report : detection of a hepatitis B surface antigen variant emerging in an elderly patient after an ischemic cerebral vascular accident. Deroux A, Larrat S, Hilleret MN, Baccard M, Qin W, Billet G, Zaoui P, Morand P. J Med Virol. 2012 Dec ;84(12):1897-900.
Performance of an antigen-antibody combined assay for hepatitis C virus testing without venipuncture. Larrat S, Bourdon C, Baccard M, Garnaud C, Mathieu S, Quesada JL, Signori-Schmuck A, Germi R, Blanc M, Leclercq P, Hilleret MN, Leroy V, Zarski JP, Morand P. J Clin Virol. 2012 Nov ;55(3):220-5.
Three-dimensional structure of the Epstein-Barr virus capsid. Germi R, Effantin G, Grossi L, Ruigrok RW, Morand P, Schoehn G. J Gen Virol. 2012 Aug ;93(Pt 8):1769-73.
Low Resolution Structure of the Vaccinia Virus DNA Replication machinery. Sèle C, Gabel F, Gutsche I, Ivanov I, Burmeister WP, Iseni F, Tarbouriech N. J Virol. 2012 Nov 21.
The structural basis for the integrity of adenovirus Ad3 dodecahedron. Szolajska E, Burmeister WP, Zochowska M, Nerlo B, Andreev I, Schoehn G, Andrieu JP, Fender P, Naskalska A, Zubieta C, Cusack S, Chroboczek J. PLoS One. 2012 ;7(9):e46075.
Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1. Elegheert J, Bracke N, Pouliot P, Gutsche I, Shkumatov AV, Tarbouriech N, Verstraete K, Bekaert A, Burmeister WP, Svergun DI, Lambrecht BN, Vergauwen B, Savvides SN. Nat Struct Mol Biol. 2012 Sep ;19(9):938-47.
The « Bridge » in the Epstein-Barr virus alkaline exonuclease protein BGLF5 contributes to shutoff activity during productive infection. Horst D, Burmeister WP, Boer IG, van Leeuwen D, Buisson M, Gorbalenya AE, Wiertz EJ, Ressing ME. J Virol. 2012 Sep ;86(17):9175-87.
The herpes simplex virus type 1 Us11 protein inhibits autophagy through its interaction with the protein kinase PKR. Lussignol M, Queval C, Bernet-Camard MF, Cotte-Laffitte J, Beau I, Codogno P, Esclatine A. J Virol. 2012 Oct 31.
[When human cytomegalovirus says STOP to autophagy : an antiviral defense mechanism]. Lussignol M, Chaumorcel M, Mouna L, Esclatine A. Med Sci (Paris). 2012 Aug-Sep ;28(8-9):698-700.
I223R mutation in influenza A(H1N1)pdm09 neuraminidase confers reduced susceptibility to oseltamivir and zanamivir and enhanced resistance with H275Y. LeGoff J, Rousset D, Abou-Jaoudé G, Scemla A, Ribaud P, Mercier-Delarue S, Caro V, Enouf V, Simon F, Molina JM, van der Werf S. PLoS One. 2012 ;7(8):e37095.
Molecular detection of respiratory viruses in immunocopromised ICU patients : incidence and meaning. Schnell D, Legoff J, Mariotte E, Seguin A, Canet E, Lemiale V, Darmon M, Schlemmer B, Simon F, Azoulay E. Respir Med. 2012 Aug ;106(8):1184-91.
T/B ratio does not reflect levels of ZAP70 expression in clonal CLL B-cells due to ZAP70 overexpression in patient T-cells. Rizzo D, Bouvier G, Youlyouz-Marfak I, Guerin E, Trimoreau F, Bordessoule D, Jaccard A, Gachard N, Feuillard J. Cytometry B Clin Cytom. 2012 Dec 6.
B7-H1, which represses EBV-immortalized B cell killing by autologous T and NK cells, is oppositely regulated by c-Myc and EBV latency III program at both mRNA and secretory lysosome levels. Durand-Panteix S, Farhat M, Youlyouz-Marfak I, Rouaud P, Ouk-Martin C, David A, Faumont N, Feuillard J, Jayat-Vignoles C. J Immunol. 2012 Jul 1 ;189(1):181-90.
Human Herpesvirus-6 cytopathic inclusions : an exceptional and recognizable finding on skin biopsy during HHV6 reactivation after autologous stem-cell transplantation. Roux J, Battistella M, Fornecker L, Legoff J, Deau B, Houhou N, Bouaziz JD, Thieblemont C, Janin A. Am J Dermatopathol. 2012 Aug ;34(6):e73-6.
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells. Lafaille FG, Pessach IM, Zhang SY, Ciancanelli MJ, Herman M, Abhyankar A, Ying SW, Keros S, Goldstein PA, Mostoslavsky G, Ordovas-Montanes J, Jouanguy E, Plancoulaine S, Tu E, Elkabetz Y, Al-Muhsen S, Tardieu M, Schlaeger TM, Daley GQ, Abel L, Casanova JL, Studer L, Notarangelo LD. Nature. 2012 Nov 29 ;491(7426):769-73.
Concepts in MDM2 Signaling : Allosteric Regulation and Feedback Loops.Ponnuswamy A, Hupp T, Fåhraeus R. Genes Cancer. 2012 Mar ;3(3-4):291-7.
The role of mRNA translation in direct MHC class I antigen presentation. Apcher S, Manoury B, Fåhraeus R. Curr Opin Immunol. 2012 Feb ;24(1):71-6.
The p53 mRNA-Mdm2 interaction controls Mdm2 nuclear trafficking and is required for p53 activation following DNA damage. Gajjar M, Candeias MM, Malbert-Colas L, Mazars A, Fujita J, Olivares-Illana V, Fåhraeus R. Cancer Cell. 2012 Jan 17 ;21(1):25-35.
A new and frequent human T-cell leukemia virus indeterminate Western blot pattern : epidemiological determinants and PCR results in central African inhabitants. Filippone C, Bassot S, Betsem E, Tortevoye P, Guillotte M, Mercereau-Puijalon O, Plancoulaine S, Calattini S, Gessain A. J Clin Microbiol. 2012 May ;50(5):1663-72.
A major locus on chromosome 3p22 conferring predisposition to human herpesvirus 8 infection. Pedergnana V, Gessain A, Tortevoye P, Byun M, Bacq-Daian D, Boland A, Casanova JL, Abel L, Plancoulaine S. Eur J Hum Genet. 2012 Jun ;20(6):690-5.
Divergent KSHV/HHV-8 subtype D strains in New Caledonia and Solomon Islands, Melanesia. Cassar O, Charavay F, Bassot S, Plancoulaine S, Grangeon JP, Laumond-Barny S, Martin PM, Chanteau S, Gessain A. J Clin Virol. 2012 Mar ;53(3):214-8.
Multicentric Castleman disease in an HHV8-infected child born to consanguineous parents with systematic review. Leroy S, Moshous D, Cassar O, Reguerre Y, Byun M, Pedergnana V, Canioni D, Gessain A, Oksenhendler E, Fieschi C, Mahlaoui N, Rivière JP, Herbigneaux RM, Muszlak M, Arnaud JP, Fischer A, Picard C, Blanche S, Plancoulaine S, Casanova JL. Pediatrics. 2012 Jan ;129(1):e199-203. doi : 10.1542/peds.2010-2739. Epub 2011 Dec 12. Review.
Disclosure of myelodysplastic syndrome diagnosis : improving patient understanding and experience.Besson C, Rannou S, Elmaaroufi H, Guirimand N, Tresvaux du Fraval F, Jenny S, Festy P, Fenaux P, Leplège A. Eur J Haematol. 2012 Dec 7.
HDP-CDV as an alternative for treatment of human herpesvirus-6 infections.. Bonnafous P, Bogaert S, Godet AN, Agut H. J Clin Virol. 2012 Nov 21.
Impact of novel mutations of herpes simplex virus 1 and 2 thymidine kinases on acyclovir phosphorylation activity. Burrel S, Bonnafous P, Hubacek P, Agut H, Boutolleau D. Antiviral Res. 2012 Dec ;96(3):386-90.
Routine use of duplex real-time PCR assays including a commercial internal control for molecular diagnosis of opportunistic DNA virus infections. Burrel S, Fovet C, Brunet C, Ovaguimian L, Hamm N, Conan F, Kalkias L, Agut H, Boutolleau D. J Virol Methods. 2012 Oct ;185(1):136-41.
Emergence of cytomegalovirus resistance to foscarnet in a patient receiving foscarnet salvage therapy for multidrug-resistant HIV infection. Boutolleau D, Canestri A, Burrel S, Wirden M, Seang S, Clavel-Osorio C, Marcelin AG, Katlama C, Agut H. J Clin Virol. 2012 Jun ;54(2):194-6.
Confirmation of the low clinical effect of human herpesvirus-6 and -7 infections after renal transplantation. Caïola D, Karras A, Flandre P, Boutolleau D, Scieux C, Agut H, Legendre C, Gautheret-Dejean A. J Med Virol. 2012 Mar ;84(3):450-6.
DsRed-mediated oligomerization stabilizes HMGB1 on chromatin in vivo and on DNA in vitro. Messmer M, Klein C, Boniface R, Gnädig NF, Lecerf M, Barnay-Verdier S, Maréchal V. Biochimie. 2012 Nov 14.
Attenuation of soft-tissue sarcomas resistance to the cytotoxic action of TNF-α by restoring p53 function. Muret J, Hasmim M, Stasik I, Jalil A, Mallavialle A, Nanbakhsh A, Lacroix L, Billot K, Baud V, Thiery J, Vielh P, Terrier P, Wiels J, Vassilev L, Lecesne A, Bonvalot S, Chouaib S. PLoS One. 2012 ;7(6):e38808.
Toll-like receptor 3 in Epstein-Barr virus-associated nasopharyngeal carcinomas : consistent expression and cytotoxic effects of its synthetic ligand poly(A:U) combined to a Smac-mimetic. Vérillaud B, Gressette M, Morel Y, Paturel C, Herman P, Lo KW, Tsao SW, Wassef M, Jimenez-Pailhes AS, Busson P. Infect Agent Cancer. 2012 Dec 3 ;7(1):36.
The human telomerase catalytic subunit and viral telomerase RNA reconstitute a functional telomerase complex in a cell-free system, but not in human cells. Trapp-Fragnet L, Marie-Egyptienne DT, Fakhoury J, Rasschaert D, Autexier C. Cell Mol Biol Lett. 2012 Dec ;17(4):598-615.
mdv1-miR-M7-5p, located in the newly identified first intron of the latency-associated transcript of Marek’s disease virus, targets the immediate-early genes ICP4 and ICP27. Strassheim S, Stik G, Rasschaert D, Laurent S. J Gen Virol. 2012 Aug ;93(Pt 8):1731-42.
Kinetic expression analysis of the cluster mdv1-mir-M9-M4, genes meq and vIL-8 differs between the lytic and latent phases of Marek’s disease virus infection. Coupeau D, Dambrine G, Rasschaert D. J Gen Virol. 2012 Jul ;93(Pt 7):1519-29.
Rho-ROCK and Rac-PAK signaling pathways have opposing effects on the cell-to-cell spread of Marek’s Disease Virus. Richerioux N, Blondeau C, Wiedemann A, Rémy S, Vautherot JF, Denesvre C. PLoS One. 2012 ;7(8):e44072.
Centromere architecture breakdown induced by the viral E3 ubiquitin ligase ICP0 protein of herpes simplex virus type 1. Gross S, Catez F, Masumoto H, Lomonte P. PLoS One. 2012 ;7(9):e44227.
HSV-1 genome subnuclear positioning and associations with host-cell PML-NBs and centromeres regulate LAT locus transcription during latency in neurons. Catez F, Picard C, Held K, Gross S, Rousseau A, Theil D, Sawtell N, Labetoulle M, Lomonte P. PLoS Pathog. 2012 ;8(8):e1002852.
Factors influencing helper-independent adeno-associated virus replication. Nicolas A, Jolinon N, Alazard-Dany N, Barateau V, Epstein AL, Greco A, Büning H, Salvetti A. Virology. 2012 Oct 10 ;432(1):1-9.
A novel monoclonal antibody for detection of galectin-9 in tissue sections : application to human tissues infected by oncogenic viruses. Barjon C, Niki T, Verillaud B, Opolon P, Bedossa P, Hirashima M, Blanchin S, Wassef M, Rosen HR, Jimenez AS, Wei M, Busson P. Infect Agent Cancer. 2012 Jul 17 ;7(1):16.
The Epstein-Barr virus BcRF1 gene product is a TBP-like protein with an essential role in late gene expression. Gruffat H, Kadjouf F, Mariamé B, Manet E. J Virol. 2012 Jun ;86(11):6023-32.
Human endogenous retrovirus type W envelope expression in blood and brain cells provides new insights into multiple sclerosis disease. Perron H, Germi R, Bernard C, Garcia-Montojo M, Deluen C, Farinelli L, Faucard R, Veas F, Stefas I, Fabriek BO, Van-Horssen J, Van-der-Valk P, Gerdil C, Mancuso R, Saresella M, Clerici M, Marcel S, Creange A, Cavaretta R, Caputo D, Arru G, Morand P, Lang AB, Sotgiu S, Ruprecht K, Rieckmann P, Villoslada P, Chofflon M, Boucraut J, Pelletier J, Hartung HP. Mult Scler. 2012 Mar 30.
Epstein-Barr virus protein EB2 stimulates cytoplasmic mRNA accumulation by counteracting the deleterious effects of SRp20 on viral mRNAs. Juillard F, Bazot Q, Mure F, Tafforeau L, Macri C, Rabourdin-Combe C, Lotteau V, Manet E, Gruffat H. Nucleic Acids Res. 2012 Aug 1 ;40(14):6834-49.
Measles virus glycoprotein-pseudotyped lentiviral vectors are highly superior to vesicular stomatitis virus g pseudotypes for genetic modification of monocyte-derived dendritic cells. Humbert JM, Frecha C, Bouafia FA, N’guyen TH, Boni S, Cosset FL, Verhoeyen E, Halary F. J Virol. 2012 May ;86(9):5192-203.
Performance of two commercially available automated immunoassays for the determination of Epstein-Barr virus serological status. Lupo J, Germi R, Semenova T, Buisson M, Seigneurin JM, Morand P. Clin Vaccine Immunol. 2012 Apr 25.
Comparison of commercial extraction systems and PCR assays for quantification of Epstein-Barr virus DNA load in whole blood. Germi R, Lupo J, Semenova T, Larrat S, Magnat N, Grossi L, Seigneurin JM, Morand P. J Clin Microbiol. 2012 Apr ;50(4):1384-9.
Inhibition of Latent Membrane Protein 1 Impairs the Growth and Tumorigenesis of Latency II Epstein-Barr Virus-Transformed T Cells. Ndour PA, Brocqueville G, Ouk TS, Goormachtigh G, Morales O, Mougel A, Bertout J, Melnyk O, Fafeur V, Feuillard J, Coll J, Adriaenssens E. J Virol. 2012 Apr ;86(7):3934-43.
Human Cytomegalovirus Entry into Dendritic Cells Occurs via a Macropinocytosis-Like Pathway in a pH-Independent and Cholesterol-Dependent Manner. Haspot F, Lavault A, Sinzger C, Laib Sampaio K, Stierhof YD, Pilet P, Bressolette-Bodin C, Halary F. PLoS One. 2012 ;7(4):e34795. Epub 2012 Apr 9.
Blood Epstein-Barr virus DNA load and risk of progression to AIDS-related systemic B lymphoma. Leruez-Ville M, Seng R, Morand P, Boufassa F, Boue F, Deveau C, Rouzioux C, Goujard C, Seigneurin J, Meyer L. HIV Med. 2012 Mar 14. doi : 10.1111/j.1468-1293.2012.00998.x.
Viral and non-viral methods to genetically modify dendritic cells. Humbert JM, Halary F. Curr Gene Ther. 2012 Apr 1 ;12(2):127-36.
Live-cell imaging reveals multiple interactions between Epstein-Barr Nuclear Antigen 1 (EBNA-1) and cellular chromatin during interphase and mitosis. Jourdan N, Jobart-Malfait A, Dos Reis G, Quignon F, Piolot T, Klein C, Tramier M, Coppey M, Marechal V. J Virol. 2012 Feb 15.
The Human Cytomegalovirus Protein TRS1 Inhibits Autophagy via Its Interaction with Beclin 1. Chaumorcel M, Lussignol M, Mouna L, Cavignac Y, Fahie K, Cotte-Laffitte J, Geballe A, Brune W, Beau I, Codogno P, Esclatine A. J Virol. 2012, 86(5):2571-84.
Nucleolin interacts with US11 protein of herpes simplex virus 1 and is involved in its trafficking. Greco A, Arata L, Soler E, Gaume X, Couté Y, Hacot S, Callé A, Monier K, Epstein AL, Sanchez JC, Bouvet P, Diaz JJ. J Virol. 2012 Feb ;86(3):1449-57.
Profiling of Epstein-Barr virus-encoded microRNAs in nasopharyngeal carcinoma reveals potential biomarkers and oncomirs. Gourzones C, Jimenez AS, Busson P. Cancer. 2012 Feb 1.
Host-tumor interactions in nasopharyngeal carcinomas. Gourzones C, Barjon C, Busson P. Semin Cancer Biol. 2012 Apr ;22(2):127-36.
Inhibition of NOTCH3 signalling significantly enhances sensitivity to cisplatin in EBV-associated nasopharyngeal carcinoma. Man CH, Wei-Man Lun S, Wai-Ying Hui J, To KF, Choy KW, Wing-Hung Chan A, Chow C, Tin-Yun Chung G, Tsao SW, Tak-Chun Yip T, Busson P, Lo KW. J Pathol. 2012 Feb ; 226(3) : 471-81.
[Complementary determination of Epstein-Barr virus DNA load and serum markers for nasopharyngeal carcinoma screening and early detection in individuals at risk in Tunisia]. Baizig NM, Morand P, Seigneurin JM, Boussen H, Fourati A, Gritli S, Oueslati Z, Touati S, Gamoudi A, Abdallah MB, El May M, May AE. Eur Arch Otorhinolaryngol. 2012 Mar ;269(3):1005-11.
[Herpes simplex encephalitis and management of acyclovir in encephalitis patients in France]. Stahl JP, Mailles A, De Broucker T ; Steering Committee and Investigators Group. Epidemiol Infect. 2012 Feb ;140(2):372-81
[Confirmation of the low clinical effect of human herpesvirus-6 and -7 infections after renal transplantation]. Caïola D, Karras A, Flandre P, Boutolleau D, Scieux C, Agut H, Legendre C, Gautheret-Dejean A. J Med Virol. 2012 Mar ;84(3):450-6. doi : 10.1002/jmv.23206.
The effect of HMGB1, a damage-associated molecular pattern molecule, on polymorphonuclear neutrophil migration depends on its concentration. Berthelot F, Fattoum L, Casulli S, Gozlan J, Maréchal V, Elbim C. J Innate Immun. 2012 ;4(1):41-58.
Identification of new interacting partners of the shuttling protein ubinuclein (Ubn-1). Lupo J, Conti A, Sueur C, Coly PA, Couté Y, Hunziker W, Burmeister WP, Germi R, Manet E, Gruffat H, Morand P, Boyer V. Exp Cell Res. 2012 Jan 4. [Epub ahead of print]
[Clinical and microbiological evaluation of travel-associated respiratory tract infections in travelers returning from countries affected by pandemic A(H1N1) 2009 influenza]. Jauréguiberry S, Boutolleau D, Grandsire E, Kofman T, Deback C, Aït-Arkoub Z, Bricaire F, Agut H, Caumes E. J Travel Med. 2012 Jan-Feb ;19(1):22-7.
[Successful treatment of aciclovir and foscarnet resistant Herpes simplex virus lesions with topical imiquimod in patients infected with human immunodeficiency virus type 1]. Lascaux AS, Caumes E, Deback C, Melica G, Challine D, Agut H, Lévy Y. J Med Virol. 2012 Feb ;84(2):194-7.
[Quantitation of human herpesvirus-6A, -6B and -7 DNAs in whole blood, mononuclear and polymorphonuclear cell fractions from healthy blood donors]. Géraudie B, Charrier M, Bonnafous P, Heurté D, Desmonet M, Bartoletti MA, Penasse C, Agut H, Gautheret-Dejean A. J Clin Virol. 2012 Feb ;53(2):151-5.
[Genotypic characterization of herpes simplex virus DNA polymerase UL42 processivity factor]. Burrel S, Aït-Arkoub Z, Agut H, Boutolleau D. Antiviral Res. 2012 Jan ;93(1):199-203.
[Chromosomally integrated human herpesvirus 6 : questions and answers]. Pellett PE, Ablashi DV, Ambros PF, Agut H, Caserta MT, Descamps V, Flamand L, Gautheret-Dejean A, Hall CB, Kamble RT, Kuehl U, Lassner D, Lautenschlager I, Loomis KS, Luppi M, Lusso P, Medveczky PG, Montoya JG, Mori Y, Ogata M, Pritchett JC, Rogez S, Seto E, Ward KN, Yoshikawa T, Razonable RR. Rev Med Virol. 2011 Nov 4. doi : 10.1002/rmv.715.